

The game begins with Aya Brea, an NYPD rookie, attending an opera with an unnamed date. The incident starts on December 24 and ends on December 29. The game takes place over a six day span in New York City in 1997. It is the first game in the Parasite Eve series.

The game is a sequel to the novel Parasite Eve, written by Hideaki Sena. Parasite Eve is a horror action role-playing game developed by SquareSoft (now Square Enix). Parasite Eve has been adapted into a 1997 film and a 1998 video game for the Sony PlayStation by Square (now Square Enix). The book was published in North America by Vertical, Inc.

Parasite Eve is a Japanese science fiction novel by Hideaki Sena, first published in Kadokawa Horror Bunko in 1996.
